Sarin, one of the world's most lethal chemical weapons, has long been stockpiled but is rarely used by states or terrorists. Allegations of attacks on civilians in Syria, if substantiated, would represent a departure from longstanding international practice, this Backgrounder explains.

The promise of a democratic Egypt faces its starkest challenge yet as a military crackdown on Islamist protestors threatens to unhinge the transition process. This Issue Guide provides background and analysis.

As the United States draws down forces in Afghanistan, the Taliban insurgency continues to challenge the government in Kabul while holding out the prospect of a negotiated settlement, explains this Backgrounder.

Ultraconservative Salafis played a prominent role in the ouster of president Mohammed Morsi, but are unlikely to shape Egypt after the transition, says expert Jonathan A.C. Brown.

Interreligious cooperation is central to facilitating transitional justice and reconciliation in Syria, says expert Daniel Philpott.

Trade liberalization, tax reform, and transparency in corporate ownership and international development are at the top of the G8 agenda, but they may be overshadowed by the civil war in Syria. This issue guide compiles news and analysis on policies on the table and member state's compliance with past years' commitments.

After over three decades of existence, the Group of Eight (G8) is struggling to defend its relevance amid criticism of its limited membership and lack of a compliance mechanism.

The future of the Muslim Brotherhood, Egypt's largest opposition movement and a standard bearer for Islamist groups around the world, remains uncertain following Mohammed Morsi's fall, explains this Backgrounder.

An end to Syria's conflict seems unlikely in the near term, as a number of obstacles on and off the battlefield have stymied international diplomatic efforts, explains this Backgrounder.

Al-Qaeda in the Arabian Peninsula has emerged as the most dangerous al-Qaeda affiliate, strengthening amid political unrest in Yemen. This Backgrounder examines the group and U.S. counterterrorism operations.