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Conflict in the Middle East could change the foreign policy course of President Obama's second term in office.

By the time President Obama renews his oath of office at the United States Capitol next January, he may have only a few short months to avoid another war in the Middle East – this one over Iran's advancing nuclear program.

The threat posed by Iran's uranium enrichment program is the most urgent example of the foreign-policy challenges that face Mr. Obama. Some, like Iran, won't wait for Inauguration Day. Others, like the use of drones or the threat of global warming, should receive new or renewed attention over the course of a second term.

Here are five overseas issues that will likely confront Obama in the next four years.

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