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Interim CDC Guidance for Nonpharmaceutical Community Mitigation in Response to Human Infections with Swine Influenza (H1N1) Virus

Published April 26, 2009

This document provides interim planning guidance for state, territorial, tribal, and local communities that focuses on several nonpharmaceutical measures that might be useful during this outbreak of swine influenza A (H1N1) virus aimed at reducing disease transmission and associated morbidity and mortality.

Human cases of swine influenza A (H1N1) virus infection have been identified in several states and in other countries.  This is a novel influenza: A virus that has not been identified in people before, and human-to-human transmission of the virus appears to be ongoing.  Unlike the experience in Mexico, the United States is currently observing a less severe clinical spectrum of disease with infection by the identical virus strain.  As of April 26, 2009, of the confirmed cases of swine influenza A (H1N1) virus infection, only two confirmed case-patients were hospitalized and none have died in the United States.   Mexican health officials have reported several hundred suspect cases, including several deaths associated with confirmed swine influenza A (H1N1) virus infection.  In Mexico, many patients have experienced rapidly progressive pneumonia, respiratory failure requiring mechanical ventilation and acute respiratory distress syndrome (ARDS).  Therefore, the experience of these two countries has been markedly different to date.  Getting better information to explain these differences is a high priority for the ongoing investigation.

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