A growing power struggle in Tehran adds new concerns for deterring Iran's nuclear ambitions. Analysts' recommendations for the U.S. range from engaging in direct talks to increasing pressure on the regime and trying to erode the regime's popular base.

Bleak assessments by the IMF and the Fed this week underlined a worsening European sovereign debt crisis and stagnant U.S. economic growth, putting renewed pressure on global financial markets and intensifying policy debate.

The assassination of Afghan government negotiator Burhanuddin Rabbani signals the challenges in any reconciliation talks with the Taliban and could exacerbate ethnic divisions, pushing the country into a civil war.

The bid for Palestinian statehood at the UN sets President Mahmoud Abbas on a collision course with Hamas, the United States, and Israel. It is crucial to get back on track to a negotiated settlement, say experts.

As Libya moves ahead with a leadership transition, it faces challenges including restarting the economy, dealing with humanitarian abuses, and the rising influence of Islamists.

Recent Taliban attacks in Kabul have undermined Afghan confidence in local security forces and cast new doubt on a sustainable transition from U.S.-led efforts, analysts say.

Investors and financial markets are growing convinced that Greece will default on its debt, heightening fears of a eurozone banking crisis that would have significant ramifications for an already fragile global economy.

Ailing U.S. infrastructure is seen as threatening U.S. competitiveness, but spending to fix it is a growing topic of debate between Republicans and Democrats as President Obama presses a new jobs program.

Sharp new fears of an escalation in eurozone debt troubles have intensified debate over whether to spur fiscal integration or risk a wider crisis with serious consequences for U.S. financial markets, experts say.

Pakistan's arrest of senior al-Qaeda leaders signals renewed cooperation with the United States. But experts stress both sides have to work harder to tackle issues such as Pakistan's relations with militant groups and U.S. objectives in Afghanistan.

This CFR Issue Guide provides expert analysis and essential background on the central questions facing U.S. policymakers ten years after the September 11 terrorist attacks.

The deadliest month for U.S. troops in Afghanistan comes to an end amid renewed debate about the U.S. endgame there and whether the nearly decade-long conflict has achieved its goals.

Libya, Syria, and Egypt headline the latest "Arab Awakening" developments. This CFR Issue Guide offers expert insight into the causes and consequences of the region's upheaval.

The debate over a new anti-corruption law in India highlights political dysfunction in New Delhi and distracts from the larger issue of an urgent need for economic reforms.

As Libyan rebels press for control of the state and the ouster of Muammar al-Qaddafi, experts warn about the troubles ahead in maintaining security and rebuilding a country emerging from forty-two years of autocratic rule.

As Vice President Joseph Biden begins a visit to China, analysts say both the United States and China will have to restructure their economies to lessen global imbalances and strengthen recovery.

International financial market upheaval continues in response to eurozone worries and the U.S. Fed's decision to keep its benchmark rate near zero until mid-2013. Analysts are divided on whether the Fed's move will curb volatility.

With markets rattled by the downgrade of U.S. debt, some experts fear running out of policy tools to prevent another global recession, while others are calling on government and central banks to improve fiscal and monetary policy coordination.

A tumultuous week in global markets that saw major indexes plunge aroused concerns of a double-dip recession driven by U.S. economic lethargy and the European Union's resurgent sovereign debt crisis.

The United States and some international partners are pressuring Damascus through the UN and other channels as the Assad regime crackdown on protesters intensifies. Expert opinion remains mixed on whether the Syrian government can be weakened.