Donald Trump and Vladimir Putin could take fresh approaches on contentious issues, including Russia’s meddling in U.S. elections, Ukraine, Syria, and arms control, to their meeting in Helsinki.

The United States has reactivated sanctions against Iran that could trigger the collapse of the multilateral Iran nuclear deal.

A collapse of this Cold War–era INF treaty, which many believe has favored the United States, could unleash a new age of nuclear weapons competition with Russia.

The United States and Russia are at odds on so many issues that the upcoming summit could convince their two presidents to give up on better relations and accept estrangement.