The U.S. health agency regulates the country’s foods and drugs, among other products. The COVID-19 pandemic and controversy over vaccines and treatments have highlighted the FDA’s role.

With the United Kingdom moving forward with Brexit, London hopes its Commonwealth partners can help boost trade, but critics say the group is outmoded and ineffective.

Here’s how different health-care systems, including single-payer and government-run, have contended with the coronavirus.