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What Comes Next After the U.S. and Israel Strike Iran?

CFR experts assess the joint U.S.–Israeli strikes on Iran, examining the implications for the region and U.S. policy. Featuring:

  • Elliott Abrams, senior fellow for Middle East Studies
  • Max Boot, Jeane J. Kirkpatrick senior fellow for National Security Studies
  • Steven A. Cook, Eni Enrico Mattei senior fellow for Middle East and Africa Studies
  • Elisa Catalano Ewers, senior fellow for Middle East Studies
  • Ray Takeyh, Hasib J. Sabbagh senior fellow for Middle East Studies

Iran, Explained

Use CFR’s backgrounders, timelines, and explainers to dig deeper into the country at the center of the U.S.–Israeli attack.

Timeline: U.S. Relations With Iran
Timeline: U.S. Relations With Iran

1953 – 2026 Onetime allies, the United States and Iran have seen tensions escalate repeatedly in the four decades since the Islamic Revolution.

<p>Iran&#8217;s Supreme Leader Ayatollah Ali Khamenei attends Eid al-Fitr prayers in Tehran, Iran on March 31, 2025.</p>
<p>Iran&#8217;s Supreme Leader Ayatollah Ali Khamenei attends Eid al-Fitr prayers in Tehran, Iran on March 31, 2025.</p>

Who calls the shots in Iran on economic policy, security, and domestic calls for reform? A look at the government’s organization chart indicates how complicated the answer is.

<p>Iranian sailors take part in the National Persian Gulf Day in the Strait of Hormuz.</p>
<p>Iranian sailors take part in the National Persian Gulf Day in the Strait of Hormuz.</p>

The narrow and congested Mideast waterway has become a site of escalating U.S.-Iran tensions. Trump’s war on Iran has placed it in the middle of the battlefield, driving a spike in oil and gas prices.

<p> Hezbollah militants parade through Beirut’s southern suburb.</p>
<p> Hezbollah militants parade through Beirut’s southern suburb.</p>
backgrounder

What Is Hezbollah?

The Iran-backed Shiite militia was considered the most powerful non-state group in the Middle East, but an Israeli military campaign against Hezbollah in 2024 has considerably weakened it.

<p>Workers on a construction site at Iran’s Bushehr nuclear power plant in November 2019. </p>
<p>Workers on a construction site at Iran’s Bushehr nuclear power plant in November 2019. </p>

Iran’s nuclear program and missile arsenal have garnered increased international scrutiny. Despite U.S. strikes on Iranian bases last year, nuclear talks between the two countries are now back on the table.      

<p>Islamic Revolutionary Guard Corps personnel in Tehran, Iran, in September 2024.</p>
<p>Islamic Revolutionary Guard Corps personnel in Tehran, Iran, in September 2024.</p>

The IRGC is one of the most powerful organizations in Iran, conceived as the principal defender of the 1979 revolution, and now a critical link to Islamist militant groups violently opposed to Israel and the United States.

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A woman holds a picture of a victim of forced disappearance during a 2025 ceremony in Colombia to honor loved ones who remain missing.
A woman holds a picture of a victim of forced disappearance during a 2025 ceremony in Colombia to honor loved ones who remain missing.

CFR International Affairs Fellow in National Security Roxanna Vigil argues that the United States should engage early with Colombia’s next administration to signal support for full implementation of the 2016 Peace Accords and provide targeted assistance.

Several U.S. naval vessels cruising on open water.
Several U.S. naval vessels cruising on open water.

CFR Senior Fellow Robert D. Blackwill outlines the conceptual pillars of five grand strategy schools and analyzes arguments for and against those strategies advanced by their proponents and critics. He then proposes an alternative American grand strategy: resolute global leadership.

<p>A Ukrainian artilleryman uses a portable rocket launcher in Ukraine’s Zaporizhzhia region on May 23, 2025.</p>
<p>A Ukrainian artilleryman uses a portable rocket launcher in Ukraine’s Zaporizhzhia region on May 23, 2025.</p>

The world continues to grow more violent and disorderly. According to CFR’s annual conflict risk assessment, American foreign policy experts are acutely concerned about conflict-related threats to U.S. national security and international stability that are likely to emerge or intensify in 2026. In this report, surveyed experts rate global conflicts by their likelihood and potential harm to U.S. interests and, for the first time, identify opportunities for preventive action.

<p>Export-bound vehicles wait to be loaded onto roll-on/roll-off ships at Lianyungang Port in China, on December 1, 2025. </p>
<p>Export-bound vehicles wait to be loaded onto roll-on/roll-off ships at Lianyungang Port in China, on December 1, 2025. </p>

The primary U.S. response to China’s first-mover advantages in emerging auto technologies has been protection. A smarter strategy would seek to compete by supporting producers and collaborating with allies, while managing security risks.

<p>A Taiwan Coast Guard ship patrols near Dadan Island in October 2025. </p>
<p>A Taiwan Coast Guard ship patrols near Dadan Island in October 2025. </p>

Assumptions about how a potential conflict between the United States and China over Taiwan would unfold should urgently be revisited. Such a war, far from being insulated, would likely draw in additional powers, expand geographically, and escalate vertically.

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